Research and Innovation

All Research and Innovation Videos

All Research and Innovation Videos

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#TomorrowsDiscoveries: Treating Prostate Cancer – Urologic Oncologist Kenneth Pienta

Urologic oncologist Kenneth Pienta and his team are working to identify what keeps disseminated tumor cells asleep or reactivates them so that they can better treat prostate cancer.

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#TomorrowsDiscoveries: Toward Less Risky Hand Transplants | Dr. W. P. Andrew Lee

#TomorrowsDiscoveries: While prosthetic limbs have limitations, transplantation can allow patients to resume normal activities. Dr. Lee and his team use a single medication that prevents immune rejection from transplanted tissues to reduce the health risks that come with transplantation.

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#TomorrowsDiscoveries: Chemotherapy-Resistant Breast Cancer Stem Cells | Dr. Gregg Semenza

Dr. Gregg Semenza’s team has identified a way to overcome the resistance of cancer stem cells to chemotherapy, completely eradicating breast tumors in mice.

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#TomorrowsDiscoveries: ‘Glitch’ that Causes Mental Disorders | Dr. Guo-li Ming

Dr. Guo-li Ming studies the biology behind brain cells, with the hope of developing new strategies for treating patients and improving their quality of life.

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#TomorrowsDiscoveries: Using Stem Cells to Treat Blood Disorders | Dr. Elias Zambidis

Dr. Elias Zambidis cares for children suffering from leukemia and other blood disorders.

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#TomorrowsDiscoveries: Energy for a Longer Life | Dr. Dan Arking

Dr. Dan Arking explores the links between the number of energy-producing mitochondria in human blood cells, genetics and frailty.

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#TomorrowsDiscoveries: Monitoring Transplanted Stem Cell Fate | Dr. Assaf Gilad

Dr. Assaf Gilad is developing new technologies to “tag” stem cells and monitor cell fate with MRI, improving patient safety and treatment outcomes, especially for those with brain cancer and heart disease.

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#TomorrowsDiscoveries: Intellectual Disability Treatments | Dr. Hans Bjornsson

Dr. Hans Bjornsson studies proteins bound to our DNA to find causes and potential treatments for a disease called Kabuki syndrome. His work may lead to one of the first treatments for an inborn intellectual disability.

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#TomorrowsDiscoveries: Giving Immune Response a Nano-Boost | Dr. Jonathan Schneck

Can a custom-built white blood cell avoid suppression by cancer and boost our immune system? Dr. Jonathan Schneck has developed “artificial antigen-presenting cells” and is working to put them to use in the clinic.

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#TomorrowsDiscoveries: Exploiting the Weakness of Mosquitoes | Christopher Potter, Ph.D.

Neuroscientist Christopher Potter and his team understand that mosquitoes pass on a disease through a simple bite. They are working to understand how an insect’s brain interprets and responds to odors.

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#TomorrowsDiscoveries: Devising Treatments to Block Rogue Genes | Dr. Philip Cole

#TomorrowsDiscoveries: Dr. Cole and his team are developing chemical techniques to block the action of disease-causing genes. They plan to use these techniques to develop new therapies.

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#TomorrowsDiscoveries: How to Eliminate Eye Drops | Dr. Peter McDonnell

Many patients worry about not being able to get their eye drops into their eyes. They may miss their eyes with squeeze bottles, or in some cases scratch their eyes.

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#TomorrowsDiscoveries: Stopping the Spread of Breast Cancer Cells | Andrew Ewald, Ph.D.

Cell biologist Andrew Ewald and his team have discovered what allows breast cancer cells to leave the main tumor and build new tumors in the lungs, bones and brains. Now, their goal is to identify patients whose breast cancer is likely to spread so they can find ways to save their lives.

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#TomorrowsDiscoveries: Healing by Regeneration | Luis Garza, M.D., Ph.D.

#TomorrowsDiscoveries: Dermatologist Luis Garza is working to reactivate the codes that allowed our cells to build our organs. Harnessing this code as adults could change typical healing from scarring to regeneration.

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#TomorrowsDiscoveries: The Hopkins Heart | Robert Higgins, M.D.

Heart failure has enormous costs, but existing therapies are often inadequate. Dr. Robert Higgins explains how a team of physicians, surgeons, engineers and biochemists are developing the next generation of replacement heart –“the Hopkins Heart.”

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#TomorrowsDiscoveries: Rebuilding Tissues and Organs | Jennifer Elisseeff, Ph.D.

Dr. Elisseeff and her team are designing scaffolds to help our bodies heal themselves after injury. Discover more at: http://www.hopkinsmedicine.org/resear...

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#TomorrowsDiscoveries: Using Technology to find Organ Donors | Andrew Cameron, M.D., Ph.D.

#TomorrowsDiscoveries: Andrew Cameron, a liver transplant surgeon, recognizes that many people wait on the transplant list. He and his team worked with Facebook to allow people to show their friends they are registered organ donors. The initiative tremendously increased donor registration rates.

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#TomorrowsDiscoveries: Strengthening Lungs before Transplants | Errol Bush, M.D.

Dr. Errol Bush and his team are developing a “lung-in-box” program to strengthen donor lungs before transplantation. Their goal is to ensure high quality of life for recipients.

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#TomorrowsDiscoveries: Therapy for Aortic Aneurysms - Dr. Hal Dietz

Johns Hopkins researchers have identified the genes responsible for aortic ballooning and the sequence of events leading to aortic aneurysms.

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#TomorrowsDiscoveries: Eliminating Harm to Patients | Dr. Peter Pronovost

#TomorrowsDiscoveries: Hospitalized patients face the potential for hundreds of complications. See how researchers at Johns Hopkins Armstrong Institute work with health care providers, engineers, psychologists and others to eliminate patient harm in healthcare. Learn more about Dr. Pronovost at http://www.hopkinsmedicine.org/profil...

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#TomorrowsDiscoveries: Using Robotic Surgery to Treat Pancreatic Cancer | Matt Weiss, M.D.

Dr. Matt Weiss and his team are developing ways to reduce the trauma of surgery to treat pancreatic cancer.

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#TomorrowsDiscoveries: Preserving Memory | Mollie K. Meffert, M.D., Ph.D.

Dr. Mollie Meffert and her team investigate how genes and electrical flow interact to strengthen connections between neurons.

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#TomorrowsDiscoveries: A Missile for Cancer | Dr. Theodore DeWeese

#TomorrowsDiscoveries: Dr. DeWeese and his team are testing a way to target a protein found on the surface of cancer cells, but not non-cancer cells. Their goal is to destroy cancer while protecting normal tissue.

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#TomorrowsDiscoveries: Why Eating Too Much Sugar Can Be Harmful | Dr. Gerald Hart

#TomorrowsDiscoveries: How does eating too much sugar lead to health problems? Dr. Hart explains the connection between dietary sugar and a unique sugar in our bodies that alters proteins’ function in response to nutrients and glucose.

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#TomorrowsDiscoveries: Connecting Heart Failure and Arrhythmias | Dr. Mark Anderson

#TomorrowsDiscoveries: Heart failure means that the heart is unable to pump enough blood, while heart arrhythmias occur when the heart’s electrical system is disorganized. Dr. Anderson and his team want to understand why heart failure and heart arrhythmias often happen together—and how both can be better prevented

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#TomorrowsDiscoveries: Toward a Treatment for Barth Syndrome | Dr. Hilary Vernon

#TomorrowsDiscoveries: Mitochondria are the powerhouses of the cell, producing the energy we need to live. So it’s no surprise that problems with mitochondria have severe effects on the body. One of these is Barth Syndrome, a failure of the immune, skeletal and cardiac systems. Dr. Hilary Vernon researches mitochondria to discover possible treatment options for Barth Syndrome.

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#TomorrowsDiscoveries: Innovative Strategies for Treating Brain Tumors | Dr. Henry Brem

#TomorrowsDiscoveries: Normal brain tissue must be protected while doctors destroy a brain tumor. Researchers at Johns Hopkins are creating new, targeted treatments for brain tumor patients.

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#TomorrowsDiscoveries: Improving Therapy for Muscle Degenerative Diseases | Dr. Elizabeth Chen

Studies of cell fusion yield insights about immunodeficiency, infertility and pathological muscle weakness. Ultimately, Dr. Elizabeth Chen’s team hopes to use these insights to improve cell-based therapy for muscle degenerative diseases.

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#TomorrowsDiscoveries: The Science Behind Memory Formation | Dr. Richard Huganir

#TomorrowsDiscoveries: Unique synapses within our brains encode new memories. See how studies on the molecular basis of memory formation can help researchers find new therapies for Alzheimer’s, age-related dementia, post-traumatic stress disorder, schizophrenia and autism.